Dr. Vikas Ghattargi*, Shikha R Kumari, Omkar B Govardhane, Shrikant P Pawar
The outburst of severe acute respiratory syndrome (SARS-COV-2) in December 2019 stumbled the mankind; the death of millions of people across the world stipulated the urge to combat COVID-19. Based on clinical data; COVID-19 along with causing upper respiratory infection managed to create gut dysbiosis and reduce immunity through gut-lung axis. Certain medication and vaccine are the current remedy; however, these are not full proof treatment to avoid COVID complications. Therefore, in this paper we highlighted the necessity to stabilize gut microbiota in order to strengthen immunity. Based on retrospective and pilot studies probiotic is proven effective as an antiviral agent or against diseases such as HIV, Influenza, Antibiotic Associated Diarrhoea and many more. In addition to this, two clinical studies and one patent filed so far provided the supportive evidence for probiotic as an alternative to combat COVID-19. Furthermore, after exploring, studying, and comparing existing statistical data we notified that the, consumption of probiotic amid COVID lessen the gut dysbiosis and re-establish beneficial gut microbiota. It also reduces the cytokine storm generated due COVID-19. Thus, it was found that probiotic enhance the immunity by increasing the count of immune cells and act as an immunomodulator and have profound effect against COVID-19. Albeit, there are supplement research data available in this field but there is still a gap in available research data and clinical studies. Henceforth, supportive clinical studies needed to be conducted to counter the limitations.
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