生物医学ジャーナル

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Impacts of SARS-Cov-2 Infection on Diabetic Patients

Rasool khan Hayat*, Shahid Ullah Zadran, Abu Zar Shinwari, Abdul Rafey Popalzai, Ubaidullah Niazi

The present pandemic of SARS-CoV-2 coronavirus disease 2019 (COVID-19) is a serious challenge to Diabetes patients. Such patients may experience mild to more severe illnesses, organ failures, comorbidities and high risk of mortality due to pulmonary and cardiac involvement. This study was carried out to investigate the effects of Covid-19 on patients with Diabetes admitted to Afghan Japan Communicable Disease Hospital, Kabul, Afghanistan. The medical records of 102 patients were reviewed who were hospitalized due to Covid-19 from March to July in 2021. Data was collected on Diabetes status, Comorbid conditions and Laboratory Results. The data was analyzed using SPSS 20 (IBM). The data analyzed shows (56.86%) were male with diabetes and (43.14%) were female, and (70%) of patients had age more than 50 years. The mortality rate was much higher than expectations (49%). The most common complications reported in diabetic patients died of COVID19 were Acute Respiratory Distress Syndrome ARDS (82%), Cardiac Pulmonary Arrest (CPA) (82%), Pneumonia (70%), Respiratory Failure (54%), Sepsis (46%), and Chronic obstructive pulmonary disease (COPD) (6%). Diabetic patients who are infected with SARS-CoV-2 are at higher risk of mortality. Our findings suggested that diabetes did not significantly impact the prognosis of Covid-19 patients but negatively affect their clinical course. Further actions should be taken to make a significant step forward in the care for Diabetes patient. Research is needed to find the molecular changes occur in expression level which leads to serious complications in diabetic patients who are infected with SARS-CoV2.

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