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COVID–19: An Emerging Disease of 21st Century

Shweta Bhodiwal*, Pankaj Yogi, Saim Pathan and Tansukh Barupal

A remarkable coronavirus termed as serious acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was disengaged from the lower respiratory tract sample as a causative agent and present a significant danger to public health. It belongs to the genus Coronavirus and placed in family Coronaviridae. Phylogenetic analysis of the complete viral genome (29,903 nucleotides) revealed that the virus was most closely related (89.1% nucleotide similarity) to a group of SARS-like coronaviruses (genus Betacoronavirus, subgenus Sarbecovirus) that had previously been found in bats in China. This disease or infection is transmitted by the inhalation or contact with infected drops and the incubation time frame goes from 2 to 14 days. The symptoms of it are normally fever, cough, breathlessness, sore throat, fatigue, malaise among others. The infection is mild in most people (mostly the older one and those with comorbidities). It might advance to pneumonia, Acute Respiratory Distress Syndrome (ARDS) and multi organ dysfunction too. Many individuals are also asymptomatic. This outbreak features the on-going capacity of viral spill-over from animals to cause serious infection in humans. This review article includes the characteristics, morphology, symptoms, clinical progression and diagnosis of corona virus.