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Burden of Cardiovascular Diseases in the Maghrebian Region, 1990-2017: Finding from the Global Burden Diseases Study 1990-2017

Zoubida Zaidi, Khaira Boussouf, Saadia Benkobbi, Cherifa Bitat-Aouati, Sabah Ben Boudiaf, Fatima Kaddour and Azzouz Djelaoudji

Background: The burden of Cardiovascular Diseases (CVD) is increasing in the Maghreb, but a systematic understanding of its distribution and time trends across the entire region is not readily available. In this report, we present a detailed analysis of how the patterns of cardiovascular diseases have changed across our region between 1990 and 2017. Methods: We analyzed the mortality and Disabilityadjusted Life-years (DALYs) due to CVD and the major component causes in the region of the Maghreb from 1990 to 2017, using all accessible data sources as part of the Global Burden of Diseases (GBD), Injuries, and Risk Factors Study 2017. We assessed heterogeneity in the burden of major CVD across the Region. We calculated 95% Uncertainty Intervals (UIs) for the point estimates. Results: Overall, CVD contributed 41, 85% (95% UI 39, 43– 46, 21) of the total deaths and 17, 70% (14, 91–19, 26) of the total DALYs in the Maghreb in 2017, from 1990 and 2017 the percentage changes of death and DALY are 30, 70% and 40, 78 %, respectively. With 158.586, 93 (95% UI 132.854, 89-176.542, 30) death number of ischemic heart disease were estimated in the Maghreb in 2017, and 38.814, 98 (95% UI 36.254, 61-43.125, 36) death number of stroke, a 2-3 times increase in both disorders from 1990. A total of 245.893, 80 CVD deaths (95% UI: 187.326, 99-380.258, 47) occurred in 2017 in the Maghreb, with the highest number in Morocco (115.124, 03) and the lowest in Mauritania (3.924, 01). Conclusion: Ischemic heart disease and stroke varies widely between the countries of the region. The agestandardized DALY rates in the Maghreb are considerably higher than the global average. These findings call for a comprehensive approach to prevent and control the burden of CVD in the region.

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