Damiano Larnè, Maria Polimeni, Rosa Basile, Mariastella Carpentieri, Saverio De Lorenzo, Giuseppe Ieropoli, Alfredo Kunkar, Santa Pellicano, Domenico Sofo, and Giuseppe Foti
Rickettsia Conorii is an obligate intracellular gram-negative bacterium that causes a spectrum of different syndromes. An 83-year-old splenectomised patient has septic shock associated with coagulopathy and multi-organ-failure. The patient is treated with doxycycline, vasoactive amines, fresh frozen plasma, antithrombin III with progressive clinical improvement. Mediterranean spotted fever is a pathology that frequently has benign characteristics however, in fragile patients it can manifest itself with severe clinical conditions.
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